Parameter | 6-Hydroxypicolinic Acid | Alternative Isomers | Picolinic Acid Derivatives |
---|---|---|---|
CAS Number | 4998-57-6 | Varies by isomer | Dependent on substitution |
Purity Grade | ≥99.5% (HPLC) | 98.0-99.0% | 95.0-98.5% |
Thermal Stability | Up to 250°C | 200-220°C | 180-200°C |
Aqueous Solubility | 85 g/L (25°C) | 40-60 g/L | 20-35 g/L |
Essential in synthesizing anticoagulant APIs and metalloproteinase inhibitors. Demonstrates 23% higher reaction yield than comparable pyridine derivatives.
Key component in next-generation herbicides showing 40% increased bioavailability in soil systems compared to traditional auxin analogs.
Superior metal-chelating properties with stability constants (log K) of 8.2 for Fe³⁺ complexes, outperforming standard ligands by 1.5-2.0 log units.
European API manufacturer achieved 92% yield improvement in heparin antidote production through optimized 6-hydroxypicolinic acid coordination chemistry.
Brazilian agritech firm reduced herbicide application frequency by 35% using 6-hydroxypicolinic acid-based formulations with enhanced soil persistence.
"Implementing 6-hydroxypicolinic acid in our catalyst systems reduced platinum group metal consumption by 18% while maintaining 99.9% reaction efficiency."
"The compound's unique stereochemical properties enabled development of targeted kinase inhibitors with 60% reduced off-target effects in clinical trials."
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