Parameter | 2-Bromo-5-hydroxypyridine | Similar Compounds |
---|---|---|
CAS Number | 55717-45-8 | 884494-94-4 (fluorinated analog) |
Molecular Formula | C5H4BrNO | C5H3BrFNO (fluorinated analog) |
Melting Point | 135.5-136.5°C | 46-47°C (trifluoromethyl derivative) |
Boiling Point | 373°C at 760 mmHg | 372.2°C (methylpyrimidine analog) |
Density | 1.788 g/cm³ | 1.333 g/cm³ (trifluoromethyl variant) |
Hazard Codes | Xi (Irritant) | R36/37/38 (Analog compounds) |
Pharmaceutical Intermediates: Critical component in synthesis of kinase inhibitors and antiviral agents.
Agrochemical Production: Building block for novel pesticides with enhanced bioactivity.
Material Science: Precursor for conductive polymers in electronic applications.
Research Applications: Key reagent in Suzuki-Miyaura cross-coupling reactions.
Used in multi-step synthesis of investigational oncology drug candidate DL-178, achieving 92% purity in final intermediate stage.
Enabled 40% yield improvement in next-generation fungicide production through optimized bromination processes.
Challenge: Required GMP-grade intermediate for Phase III clinical trial material
Solution: Supplied 98.5% purity material with full ICH stability documentation
Outcome: Accelerated regulatory submission timeline by 14 weeks
Challenge: Scalability issues in pilot plant production
Solution: Customized purification protocol reducing byproducts by 67%
Outcome: Achieved commercial-scale production within 8 months
For batch-specific specifications or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
Include:
- Required quantity & purity
- Application sector (pharma/agro/materials)
- Timeline requirements
- Any special packaging/storage needs
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