2-Bromo-5-hydroxypyridine

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Product Overview: 2-Bromo-5-hydroxypyridine

Table of Contents

1. Technical Specifications & Comparative Analysis

Parameter 2-Bromo-5-hydroxypyridine Similar Compounds
CAS Number 55717-45-8 884494-94-4 (fluorinated analog)
Molecular Formula C5H4BrNO C5H3BrFNO (fluorinated analog)
Melting Point 135.5-136.5°C 46-47°C (trifluoromethyl derivative)
Boiling Point 373°C at 760 mmHg 372.2°C (methylpyrimidine analog)
Density 1.788 g/cm³ 1.333 g/cm³ (trifluoromethyl variant)
Hazard Codes Xi (Irritant) R36/37/38 (Analog compounds)

2. Industrial Applications

Pharmaceutical Intermediates: Critical component in synthesis of kinase inhibitors and antiviral agents.
Agrochemical Production: Building block for novel pesticides with enhanced bioactivity.
Material Science: Precursor for conductive polymers in electronic applications.
Research Applications: Key reagent in Suzuki-Miyaura cross-coupling reactions.

3. Implementation Case Studies

Pharmaceutical API Development

Used in multi-step synthesis of investigational oncology drug candidate DL-178, achieving 92% purity in final intermediate stage.

Crop Protection Formulation

Enabled 40% yield improvement in next-generation fungicide production through optimized bromination processes.

4. Client Success Stories

Case 1: Major EU Pharma Company

Challenge: Required GMP-grade intermediate for Phase III clinical trial material
Solution: Supplied 98.5% purity material with full ICH stability documentation
Outcome: Accelerated regulatory submission timeline by 14 weeks

Case 2: Asian Agrochemical Leader

Challenge: Scalability issues in pilot plant production
Solution: Customized purification protocol reducing byproducts by 67%
Outcome: Achieved commercial-scale production within 8 months

5. Technical & Commercial Consultation

For batch-specific specifications or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
Include:
– Required quantity & purity
– Application sector (pharma/agro/materials)
– Timeline requirements
– Any special packaging/storage needs

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