N-Benzylcinchonidinium chloride

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N-Benzylcinchonidinium Chloride: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 69257-04-7
Molecular Formula C₂₆H₂₉ClN₂
Molecular Weight 433.97 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Storage Conditions 2-8°C in dry environment

2. Key Applications & Industrial Uses

Primary applications in asymmetric synthesis:

  • Chiral phase-transfer catalyst in enantioselective alkylation
  • Critical component in pharmaceutical intermediates production
  • Asymmetric epoxidation of α,β-unsaturated ketones
  • Resolution of racemic mixtures in fine chemical synthesis

3. Technical Parameter Comparison

Feature N-Benzylcinchonidinium Cl Standard Cinchona Alkaloids
Catalytic Efficiency High (90-95% ee) Moderate (70-85% ee)
Reaction Temperature -20°C to 40°C 0°C to 25°C
Solvent Compatibility Wider range (including toluene/water systems) Limited to specific solvent pairs

4. Operational Guidelines

Optimal usage protocols:

  1. Recommended dosage: 5-10 mol% of substrate
  2. Pre-activation: Stir in dichloromethane for 30 mins at 25°C
  3. Typical reaction time: 12-48 hours
  4. Post-recovery: Acid-base extraction method (85% recovery rate)

5. Case Studies & Client Success Stories

Case 1: Pharmaceutical Intermediate Production

Client: EuroPharma Solutions

  • Application: Synthesis of β-amino alcohol derivatives
  • Result: Achieved 92% enantiomeric excess
  • Output Increase: 40% yield improvement vs. previous catalysts

Case 2: Agrochemical Research

Client: AgroChem Research Institute

  • Application: Asymmetric synthesis of chiral fungicide precursors
  • Result: Reduced byproducts by 65%
  • Process Cost: 30% reduction in purification expenses

6. Request Customized Solutions

Contact our technical team for application-specific support:

Email: info@vivalr.com
Phone: (86) 15866781826

Request parameters:

  • Target reaction type
  • Substrate characteristics
  • Preferred scale (lab/pilot/production)
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