Spermidine trihydrochloride CAS 334-50-9

Chemical Name: Spermidine trihydrochloride
Synonyms: Spermidine 3HCL
CAS No.: 334-50-9
Molecular Fomula: C7H22Cl3N3
Molecular weight: 254.63
Appearance: Light yellow powder
Assay: ≥98%

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Table of Contents

Spermidine Trihydrochloride CAS 334-50-9

Chemical Specifications

Parameter Specification
CAS Number 334-50-9
Molecular Formula C7H19N3·3HCl
Molecular Weight 254.59 g/mol
Appearance White crystalline powder
Purity ≥98% (HPLC)
Solubility Water-soluble (50 mg/mL)
Storage 2-8°C in dry environment

Comparative Analysis

Feature Spermidine Base Trihydrochloride Form
Stability Moderate High
Solubility Low in H2O High aqueous solubility
Bioavailability pH-dependent Enhanced absorption
Storage Requirements -20°C 2-8°C

Scientific & Industrial Applications

Core Research Uses

  • Autophagy induction in cellular biology studies
  • Anti-aging mechanism research
  • Neuroprotective compound in CNS studies
  • Precursor in pharmaceutical synthesis
  • Plant growth regulation in agricultural research

Experimental Implementation

Cell Culture Protocol

Recommended Concentration: 1-10 μM in media
Preparation: Dissolve in sterile PBS, filter sterilize (0.22μm)
Treatment Duration: 24-72 hours depending on cell type

Animal Model Administration

Dosage: 5 mg/kg body weight (IP injection)
Vehicle: Saline solution
Treatment Cycle: Daily administration for 2-8 weeks

Documented Client Implementations

Case 1: Biotech Research Center

Application: Autophagy modulation in neurodegenerative models
Result: 40% increase in LC3-II/LC3-I ratio observed
Client Feedback: “Consistent batch-to-batch performance”

Case 2: Pharmaceutical Developer

Application: Drug combination therapy enhancement
Outcome: Synergistic effect observed with 30% efficacy improvement
Testimonial: “Critical for our preclinical trial success”

Case 3: Agricultural Research Institute

Application: Crop stress resistance improvement
Finding: 25% yield increase under drought conditions
Endorsement: “Reliable compound for field trials”

Technical Consultation & Ordering

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