1. Product Overview & Specifications

6-Bromoquinazolin-4-ol (CAS: 32084-59-6) is a brominated quinazoline derivative widely used as a pharmaceutical intermediate and organic synthesis building block. Its molecular formula is C₈H₅BrN₂O, with a molecular weight of 225.04 g/mol.

2. Key Applications

• Pharmaceutical Intermediates: Critical in synthesizing kinase inhibitors and anticancer agents.
• Agrochemical Research: Used to develop novel herbicides and fungicides.
• Organic Synthesis: Serves as a versatile building block for heterocyclic compounds.

3. Usage Guidelines

1. Handle under inert gas (e.g., N₂) to prevent oxidation.
2. Use anhydrous solvents for reactions requiring moisture-sensitive conditions.
3. Optimize reaction temperatures between 80-120°C for coupling reactions.

4. Case Studies

Case 1: Anticancer Drug Development

A research team utilized 6-Bromoquinazolin-4-ol to synthesize EGFR inhibitors, achieving 85% yield in palladium-catalyzed cross-coupling reactions.

Case 2: Herbicide Formulation

An agrochemical company incorporated this compound into a novel herbicide, demonstrating 92% weed suppression in field trials.

5. Customer Success Stories

PharmaTech Solutions

Reduced synthesis steps for a lead compound by 40% using 6-Bromoquinazolin-4-ol as key intermediate.

BioAgro Innovations

Developed a patent-pending fungicide formulation with enhanced stability using this quinazoline derivative.

6. Contact for Custom Solutions

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