Parameter | 2-Iodopyridine | 2-Bromopyridine | 2-Chloropyridine |
---|---|---|---|
CAS Number | 18511-71-2 | 3510-66-5 | 109-09-1 |
Molecular Formula | C5H4IN | C5H4BrN | C5H4ClN |
Molecular Weight | 205.00 g/mol | 158.00 g/mol | 113.55 g/mol |
Appearance | White to pale yellow crystals | Colorless liquid | Colorless liquid |
Purity | ≥98% (HPLC) | ≥97% | ≥99% |
Storage Conditions | 2-8°C in dark place | Room temperature | Room temperature |
Widely used in Suzuki-Miyaura cross-coupling reactions for synthesizing:
Client: PharmaTech Inc. (USA)
Challenge: Required high-purity 2-iodopyridine for scale-up synthesis of BTK inhibitor candidates
Solution: Supplied 99.5% HPLC-grade material with complete analytical documentation
Outcome: Achieved 92% yield in key coupling reaction, accelerated preclinical timeline by 3 months
Client: Lumina Materials Co., Ltd. (South Korea)
Challenge: Needed consistent batch quality for electron-transport layer development
Solution: Customized packaging with nitrogen atmosphere protection
Outcome: Improved device efficiency by 15% compared to previous brominated analogs
Client: AgroSolutions GmbH (Germany)
Challenge: Required stable iodine-containing intermediate for novel fungicide
Solution: Technical consultation + bulk supply with just-in-time delivery
Outcome: Successful field trials with 40% higher efficacy than commercial benchmarks
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