Imidazo[1,2-b]pyridazine: Comprehensive User Guide for Pharmaceutical and Research Applications
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Imidazo[1,2-b]pyridazine | Analogous Compounds |
|---|---|---|
| CAS Number | 1317470-48-6 | Varies by structure |
| Molecular Formula | C7H6N4 | Typically C6-9H5-12N3-5 |
| Purity Grade | ≥99.5% (HPLC) | 90-98% (typical competitors) |
| Solubility | DMSO: 50 mg/mL Water: <1 mg/mL |
Limited aqueous solubility common |
2. Pharmaceutical Applications & Research Implementations
2.1 Kinase Inhibition Development
As privileged scaffold in:
- JAK/STAT pathway inhibitors
- BTK kinase targeting compounds
- c-Met tyrosine kinase blockers
2.2 Antibacterial Agent Discovery
Demonstrated MIC values:
- 3.12 μg/mL against S. aureus (MRSA)
- 6.25 μg/mL vs E. coli (ESBL-producing)
3. Documented Industry Success Stories
Case Study 1: Oncology Therapeutics Development
Client: Top 10 Pharma Company (Confidential)
- Application: PARP inhibitor scaffold modification
- Result: 45% improvement in binding affinity vs benchmark
- Scale: 22 kg GMP-grade material delivered
Case Study 2: Agricultural Chemistry Innovation
Client: AgChem Solutions Ltd.
- Use: Fungicidal activity optimization
- Outcome: 78% disease suppression at 50 ppm
- Regulatory: EPA approval achieved Q3 2023
4. Technical Support & Ordering Details
Request Custom Synthesis or Bulk Pricing:
- ✉️ Email: info@vivalr.com
- Tel: (86) 15866781826
Same-day quotation response · 48hr sample delivery · Regulatory documentation support
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