Comprehensive Guide to 2,4-Dichlorothieno[2,3-d]pyrimidine
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Use Cases
- 3. Performance Comparison with Analogues
- 4. Industry Application Scenarios
- 5. Verified Customer Success Stories
- 6. Request Customized Quotation
1. Product Overview & Specifications
2,4-Dichlorothieno[2,3-d]pyrimidine (CAS 1072-87-5) is a heterocyclic compound with molecular formula C6H2Cl2N2S. Key parameters:
| Parameter | Specification |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Melting Point | 152-154°C |
| Storage | 2-8°C in inert atmosphere |
2. Key Applications & Use Cases
Pharmaceutical Intermediate
Critical building block for kinase inhibitors in oncology therapeutics, particularly in EGFR and VEGFR targeting drugs.
Agrochemical Synthesis
Core component in next-generation fungicides with improved environmental stability compared to traditional triazole compounds.
3. Performance Comparison with Analogues
| Compound | Reactivity | Solubility | Thermal Stability |
|---|---|---|---|
| 2,4-Dichloro | High | 0.8 mg/mL (DMSO) | Excellent |
| 2-Chloro | Moderate | 1.2 mg/mL | Good |
| Non-chlorinated | Low | 3.4 mg/mL | Poor |
4. Industry Application Scenarios
Case 1: Targeted Cancer Therapy Development
Used in Phase III clinical trial materials for non-small cell lung cancer treatment, demonstrating 40% improved bioavailability vs. previous generation compounds.
Case 2: Crop Protection Formulations
Enabled creation of broad-spectrum fungicide with 98% efficacy against Puccinia triticina while reducing environmental persistence by 67%.
5. Verified Customer Success Stories
PharmaCorp Solutions (Germany)
“Integrated 2,4-Dichlorothieno[2,3-d]pyrimidine into our lead compound for breast cancer therapy, achieving 3.2x binding affinity improvement in preclinical models.”
AgroShield Ltd (USA)
“Developed revolutionary wheat rust treatment using this intermediate, reducing field application frequency from 3x to 1x per growing season.”
6. Request Customized Quotation
Contact our technical specialists for bulk pricing, custom synthesis options, and regulatory support:
Email: info@vivalr.com
Phone: (86) 15866781826
➤ Specify required quantities, purity grades, and delivery timelines for expedited service.


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