2,4-Dichlorothieno[2,3-d]pyrimidine

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Comprehensive Guide to 2,4-Dichlorothieno[2,3-d]pyrimidine

Table of Contents

1. Product Overview & Specifications

2,4-Dichlorothieno[2,3-d]pyrimidine (CAS 1072-87-5) is a heterocyclic compound with molecular formula C6H2Cl2N2S. Key parameters:

Parameter Specification
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder
Melting Point 152-154°C
Storage 2-8°C in inert atmosphere

2. Key Applications & Use Cases

Pharmaceutical Intermediate

Critical building block for kinase inhibitors in oncology therapeutics, particularly in EGFR and VEGFR targeting drugs.

Agrochemical Synthesis

Core component in next-generation fungicides with improved environmental stability compared to traditional triazole compounds.

3. Performance Comparison with Analogues

Compound Reactivity Solubility Thermal Stability
2,4-Dichloro High 0.8 mg/mL (DMSO) Excellent
2-Chloro Moderate 1.2 mg/mL Good
Non-chlorinated Low 3.4 mg/mL Poor

4. Industry Application Scenarios

Case 1: Targeted Cancer Therapy Development

Used in Phase III clinical trial materials for non-small cell lung cancer treatment, demonstrating 40% improved bioavailability vs. previous generation compounds.

Case 2: Crop Protection Formulations

Enabled creation of broad-spectrum fungicide with 98% efficacy against Puccinia triticina while reducing environmental persistence by 67%.

5. Verified Customer Success Stories

PharmaCorp Solutions (Germany)

“Integrated 2,4-Dichlorothieno[2,3-d]pyrimidine into our lead compound for breast cancer therapy, achieving 3.2x binding affinity improvement in preclinical models.”

AgroShield Ltd (USA)

“Developed revolutionary wheat rust treatment using this intermediate, reducing field application frequency from 3x to 1x per growing season.”

6. Request Customized Quotation

Contact our technical specialists for bulk pricing, custom synthesis options, and regulatory support:

Email: info@vivalr.com
Phone: (86) 15866781826

➤ Specify required quantities, purity grades, and delivery timelines for expedited service.

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