1. Product Overview & Specifications

6-Chloro-4-hydroxyquinazoline (CAS 1078-30-4) is a quinazoline derivative widely used in pharmaceutical research and organic synthesis. Key parameters:

Comparative Analysis

2. Key Applications

• Kinase Inhibitor Development: Intermediate for EGFR/VEGFR inhibitors
• Anticancer Agents: Backbone for DNA-intercalating compounds
• Antimicrobial Research: Precursor for quinolone derivatives
• Organic Synthesis: Building block for heterocyclic compounds

3. Usage Scenarios

Case 1: EGFR Inhibitor Synthesis

Used in 3-step synthesis of erlotinib analogs, achieving 72% yield under optimized Pd-catalyzed coupling conditions.

Case 2: Antiparasitic Drug Development

Functionalized to create novel compounds with IC₅₀ = 1.2 μM against Plasmodium falciparum.

4. Customer Case Studies

PharmaGen Solutions (2023)

• Challenge: Required high-purity intermediate for Phase II oncology trials
• Solution: Custom synthesis with >99.5% purity
• Outcome: Accelerated IND submission by 11 weeks

BioHealth Innovations (2024)

• Challenge: Scale-up from gram to kilogram quantities
• Solution: Optimized crystallization process
• Outcome: Reduced production costs by 34%

5. Request a Quote

Contact our technical team for batch-specific COA, pricing, and custom synthesis options:

info@vivalr.com
(86) 15866781826

Why Choose Us?
– ISO 9001-certified production
– 48-hour quotation service
– Regulatory support for FDA/EMA submissions