3-Amino-5-bromo-2-chloropyridine

  ... 正在查看此商品

  分享
Guaranteed Safe Checkout

3-Amino-5-bromo-2-chloropyridine: Comprehensive User Guide

1. Product Overview & Specifications

Parameter Specification
Chemical Name 3-Amino-5-bromo-2-chloropyridine
CAS Number 588729-99-1
Molecular Formula C5H4BrClN2
Molecular Weight 207.456 g/mol
Density 1.8±0.1 g/cm³
Boiling Point 296.8±35.0 °C
Flash Point 133.3±25.9 °C
Refractive Index 1.648

Key Features: High-purity intermediate (≥99%) with stability under controlled storage (4°C, protected from light).

2. Applications & Industrial Uses

Core Applications:

  • Pharmaceutical Intermediates: Critical in synthesizing active pharmaceutical ingredients (APIs) for antiviral and anticancer drugs.
  • Agrochemicals: Used to develop herbicides and fungicides due to its halogenated pyridine backbone.
  • Dye Manufacturing: Serves as a precursor for lightfast organic dyes in textiles and coatings.
  • Organic Synthesis: Facilitates cross-coupling reactions (e.g., Suzuki-Miyaura) in research and industrial processes.

3. Operational Guidelines

Recommended Workflow:

  1. Storage: Store at 4°C in airtight, light-resistant containers. Avoid prolonged exposure to moisture.
  2. Handling: Use PPE (gloves, goggles, lab coat) in fume hoods to minimize inhalation/contact risks.
  3. Reaction Conditions: Optimize at temperatures below 200°C to prevent decomposition. Compatible with THF, DCM, and DMF solvents.

4. Safety & Handling Protocols

Hazard Precaution
Skin/Irritation Wash immediately with soap/water. Seek medical attention if irritation persists.
Eye Exposure Rinse eyes with water for 15 minutes. Remove contact lenses if present.
Inhalation Move to fresh air. Administer oxygen if breathing difficulties occur.

GHS Classification: Skin Irritant (Category 2), Eye Damage (Category 2A).

5. Client Case Studies

Case Study 1: Pharmaceutical R&D Firm

Challenge: Required a stable intermediate for a kinase inhibitor synthesis.

Solution: Integrated 3-Amino-5-bromo-2-chloropyridine into Pd-catalyzed coupling steps, achieving 92% yield.

Case Study 2: Agrochemical Manufacturer

Challenge: Needed a cost-effective precursor for a novel fungicide.

Solution: Scaled up production using this compound, reducing synthesis steps by 30%.

6. Contact for Quotation

Request pricing, bulk orders, or technical support:

0.00
0 条评论
5
0
4
0
3
0
2
0
1
0
成为第一个评论 “3-Amino-5-bromo-2-chloropyridine”

您的邮箱地址不会被公开。 必填项已用 * 标注

这是必填栏。

这是必填栏。

这是必填栏。

评论

目前还没有评论。

类别 
我的购物车
愿望清单
最近浏览
类别
Wait! before you leave…
Get 30% off for your first order
CODE30OFFCopy to clipboard
Use above code to get 30% off for your first order when checkout
比较产品 (0 产品)