2-Fluoro-4-Nitropyridine (CAS 14917-41-2) is a fluorinated pyridine derivative widely used in pharmaceutical synthesis and agrochemical research. Key parameters:
Parameter | Specification | Competitor A | Competitor B |
---|---|---|---|
Purity | ≥99% | ≥98% | ≥97.5% |
Appearance | Yellow crystalline powder | Off-white powder | Pale yellow solid |
Solubility | Soluble in DMSO, DMF | Partial solubility | Limited solubility |
Used in synthesis of kinase inhibitors and antiviral agents due to its electron-withdrawing nitro group.
Critical component in developing next-gen herbicides with enhanced bioavailability.
Step 1: React with aminopyridine under Pd catalysis (80°C, 12hr)
Yield: 82% (vs. industry average 75%)
Challenge: Improve solubility of lead compound
Solution: Used 2-Fluoro-4-Nitropyridine as directing group
Result: 40% solubility improvement
Challenge: Develop low-toxicity herbicide
Solution: Created fluorinated analog using our compound
Result: Reduced environmental persistence by 60%
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