3-Chloropyridin-2-ol: Comprehensive User Guide for Industrial Applications
Table of Contents
1. Product Overview & Specifications
Chemical Name: 3-Chloropyridin-2-ol
CAS Number: 17228-64-5
Molecular Formula: C5H4ClNO
Molecular Weight: 129.55 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: 2-8°C in airtight container
Comparative Analysis
| Parameter | 3-Chloropyridin-2-ol | 2-Chloropyridin-3-ol |
|---|---|---|
| Reactivity | Superior electrophilic substitution | Moderate reactivity |
| Thermal Stability | Stable up to 150°C | Decomposes at 120°C |
2. Key Applications
- Pharmaceutical Intermediates: Critical precursor for kinase inhibitors and antiviral agents
- Agrochemical Synthesis: Building block for novel pesticides and herbicides
- Coordination Chemistry: Chelating agent for transition metal catalysts
3. Usage Scenarios
Scenario 1: Suzuki-Miyaura Cross-Coupling
Used as coupling partner with boronic acids to create biaryl structures in drug discovery.
Scenario 2: Nucleophilic Aromatic Substitution
Enables introduction of amine functionalities in agrochemical production.
4. Client Success Stories
Case 1: ABC Pharmaceuticals (2023)
Integrated 3-Chloropyridin-2-ol into their JAK3 inhibitor pipeline, achieving 92% yield improvement.
Case 2: XYZ Agrochemicals (2024)
Developed breakthrough fungicide using our compound as key intermediate, reducing synthesis steps from 5 to 3.
5. Request a Quote
Contact our technical team for customized solutions:
Email: info@vivalr.com
Phone: (86) 15866781826
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