Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Usage Guidelines & Safety Protocols
- 4. Verified Client Case Studies
- 5. Request Customized Solutions
1. Product Overview & Specifications
2-Hydroxy-4-methyl-5-nitropyridine (CAS 21953-42-6)
| Parameter | Specification | Comparison with 3-Nitro-4-hydroxypyridine |
|---|---|---|
| Molecular Formula | C6H6N2O3 | Same backbone, different substituent positions |
| Purity | ≥99% (HPLC) | Higher thermal stability |
| Melting Point | 162-165°C | 15°C lower than isomer |
| Solubility | DMSO >100mg/mL | Better organic solvent compatibility |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
Critical precursor for:
- EGFR inhibitor development (85% of oncology research applications)
- Antibacterial quinolone derivatives
Coordination Chemistry
Preferred ligand for:
- Ruthenium-based catalysis systems
- Rare earth element separation
3. Usage Guidelines & Safety Protocols
Handling Requirements
- Storage: Nitrogen atmosphere at 2-8°C
- PPE: Chemical goggles + Class III ventilators
Reaction Optimization
- Optimal pH range: 6.8-7.2
- Catalyst pairing: Pd/C shows 23% higher yield vs Pt
4. Verified Client Case Studies
Case 1: Anticancer Drug Development
Client: Top 10 Global Pharma Company
- Application: Third-generation TKIs intermediate
- Result: Achieved 92% purity in final API
Case 2: OLED Material Synthesis
Client: Electronic Materials Manufacturer
- Outcome: 15% improvement in electron mobility
- Scale: 500kg/month production
5. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (50kg+ orders)
- Custom synthesis services
- Regulatory support (REACH, FDA DMF)
Email: info@vivalr.com
Tel: (86) 15866781826


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