2,4-Dichloro-5-fluoropyrimidine

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Comprehensive Guide to 2,4-Dichloro-5-fluoropyrimidine

Table of Contents

1. Product Overview

Parameter Specification
CAS Number 2927-71-5
Molecular Formula C4HCl2FN2
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder
Storage Conditions 2-8°C in sealed containers

2. Parameter Comparison

Supplier Purity Packaging Lead Time
Supplier A 95% 1kg foil bags 4 weeks
Supplier B 97% 500g glass bottles 6 weeks
VIVALR Standard 99% Customized packaging 2 weeks

3. Key Applications

Pharmaceutical Intermediates

Essential component in synthesis of:

  • Anticancer agents (EGFR inhibitors)
  • Antiviral medications
  • Kinase inhibitor precursors

Agrochemical Development

Key building block for:

  • Herbicide formulations
  • Fungicide active ingredients
  • Plant growth regulators

4. Industrial Case Studies

Case 1: Antiviral Drug Synthesis

Used in 7-step synthesis process for Sofosbuvir intermediate production:

  • Yield improvement: 62% → 78%
  • Reaction time reduction: 48h → 32h

Case 2: Herbicide Formulation

Development of next-generation broad-spectrum herbicide:

  • Field efficacy improvement: 89% weed control
  • Reduced environmental persistence

5. Usage Guidelines

Parameter Recommendation
Handling Use under nitrogen atmosphere
Reaction Solvents DCM/THF mixtures (1:3 ratio)
Catalyst Systems Pd(PPh3)4/CuI combinations

6. Client Implementation Examples

Pharmaceutical Manufacturer (EU)

  • Application: Tyrosine kinase inhibitor production
  • Annual Consumption: 850kg
  • Result: 22% production cost reduction

Agro Research Facility (USA)

  • Project: Novel pre-emergent herbicide
  • Technical Support: Custom purity optimization
  • Outcome: Successful EPA registration

7. Contact for Technical Consultation

Request custom synthesis specifications or bulk pricing:

Key Advantages:

  • GMP-compliant production
  • ISO 9001:2015 certified facilities
  • 24/7 technical support team
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