Chemical Name: FMOC-O-tert-Butyl-L-serine
CAS No.: 71989-33-8
Appearance: White powder
Assay:≥99.0
Parameter | FMOC-O-tert-Butyl-L-serine | Standard Amino Acid Derivatives |
---|---|---|
CAS Number | 71989-33-8 | Varies |
Molecular Formula | C22H25NO5 | Typically C9-C20 |
Molecular Weight | 383.44 g/mol | 200-400 g/mol |
Melting Point | 130.5-135.5°C | 100-250°C |
Solubility | DCM, Chloroform, Acetone, DMSO | Polar aprotic solvents |
This Fmoc-protected serine derivative serves critical functions in:
Storage: Maintain at 2-8°C in airtight containers
Handling: Use under inert atmosphere (N2/Ar) with appropriate PPE
Purification: Recommended chromatography methods: HPLC (C18 columns), flash chromatography
Case 1: Enabled synthesis of antimicrobial peptides with 92% yield in a GMP facility
Case 2: Key intermediate in oncology drug development (Phase II clinical trials)
PharmaTech Solutions: Achieved 40% cost reduction in peptide API production through optimized FMOC chemistry
BioSynth Laboratories: Scaled synthesis to 50kg batches with 99.5% purity for commercial applications
For bulk pricing, SDS, or synthesis protocols:
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