FMOC-O-tert-Butyl-L-serine CAS 71989-33-8

Chemical Name: FMOC-O-tert-Butyl-L-serine
CAS No.: 71989-33-8
Appearance: White powder
Assay：≥99.0

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FMOC-O-tert-Butyl-L-serine (CAS 71989-33-8) Comprehensive Guide

Parameter	FMOC-O-tert-Butyl-L-serine	Standard Amino Acid Derivatives
CAS Number	71989-33-8	Varies
Molecular Formula	C₂₂H₂₅NO₅	Typically C₉-C₂₀
Molecular Weight	383.44 g/mol	200-400 g/mol
Melting Point	130.5-135.5°C	100-250°C
Solubility	DCM, Chloroform, Acetone, DMSO	Polar aprotic solvents

This Fmoc-protected serine derivative serves critical functions in:

Storage: Maintain at 2-8°C in airtight containers

Handling: Use under inert atmosphere (N₂/Ar) with appropriate PPE

Purification: Recommended chromatography methods: HPLC (C18 columns), flash chromatography

Case 1: Enabled synthesis of antimicrobial peptides with 92% yield in a GMP facility

Case 2: Key intermediate in oncology drug development (Phase II clinical trials)

PharmaTech Solutions: Achieved 40% cost reduction in peptide API production through optimized FMOC chemistry

BioSynth Laboratories: Scaled synthesis to 50kg batches with 99.5% purity for commercial applications

For bulk pricing, SDS, or synthesis protocols:

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