4-Amino-5-chloro-2,6-dimethylpyrimidine (CAS 858149-75-4) is a high-purity heterocyclic compound widely used in pharmaceutical and agrochemical synthesis. Key parameters:
Parameter | Specification |
---|---|
Molecular Formula | C6H9ClN4 |
Molecular Weight | 172.62 g/mol |
Purity | ≥98% (HPLC) |
Appearance | White to off-white crystalline powder |
Storage | 2-8°C in airtight container |
Critical component in synthesizing kinase inhibitors and antiviral agents. Demonstrates superior reactivity in Suzuki-Miyaura cross-coupling reactions compared to analogous pyrimidine derivatives.
Used in production of systemic fungicides with 20-30% higher bioavailability than traditional chloropyrimidines.
Building block for OLED materials, showing enhanced electron-transport properties in recent studies (2023 Journal of Materials Chemistry).
Challenge: Required stable intermediate for COVID-19 protease inhibitor development.
Solution: Implemented our compound in Pd-catalyzed amination reactions
Result: Achieved 92% yield improvement vs. previous intermediates
Challenge: Needed low-toxicity fungicide precursor
Solution: Used batch-traceable 4-Amino-5-chloro-2,6-dimethylpyrimidine
Result: Reduced synthesis steps from 7 to 4 with 99.5% purity
Parameter | Our Product | Generic Alternatives |
---|---|---|
Thermal Stability | Stable up to 250°C | Degrades at 180-200°C |
Solubility (DMSO) | 85 mg/mL | 40-60 mg/mL |
Shelf Life | 36 months | 12-18 months |
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