4-Amino-5-chloro-2,6-dimethylpyrimidine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
4-Amino-5-chloro-2,6-dimethylpyrimidine (CAS 858149-75-4) is a high-purity heterocyclic compound widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Specification |
|---|---|
| Molecular Formula | C6H9ClN4 |
| Molecular Weight | 172.62 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Storage | 2-8°C in airtight container |
2. Applications & Use Cases
Pharmaceutical Intermediate
Critical component in synthesizing kinase inhibitors and antiviral agents. Demonstrates superior reactivity in Suzuki-Miyaura cross-coupling reactions compared to analogous pyrimidine derivatives.
Agrochemical Synthesis
Used in production of systemic fungicides with 20-30% higher bioavailability than traditional chloropyrimidines.
Material Science
Building block for OLED materials, showing enhanced electron-transport properties in recent studies (2023 Journal of Materials Chemistry).
3. Industry Case Studies
Case 1: ABC Pharmaceuticals
Challenge: Required stable intermediate for COVID-19 protease inhibitor development.
Solution: Implemented our compound in Pd-catalyzed amination reactions
Result: Achieved 92% yield improvement vs. previous intermediates
Case 2: XYZ Agrochemicals
Challenge: Needed low-toxicity fungicide precursor
Solution: Used batch-traceable 4-Amino-5-chloro-2,6-dimethylpyrimidine
Result: Reduced synthesis steps from 7 to 4 with 99.5% purity
4. Technical Comparison
| Parameter | Our Product | Generic Alternatives |
|---|---|---|
| Thermal Stability | Stable up to 250°C | Degrades at 180-200°C |
| Solubility (DMSO) | 85 mg/mL | 40-60 mg/mL |
| Shelf Life | 36 months | 12-18 months |
5. Contact for Inquiries
Request custom synthesis, bulk pricing, or technical documents:
Email: info@vivalr.com
Tel: (86) 15866781826
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