2-Bromo-4-chloropyridine: Technical Guide & Industry Applications
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 2-Bromo-4-chloropyridine | 2-Chloro-4-bromopyridine | 2-Bromo-4-fluoropyridine |
|---|---|---|---|
| CAS Number | 514797-18-5 | 102071-13-8 | 1003741-91-6 |
| Molecular Formula | C5H3BrClN | C5H3BrClN | C5H3BrFN |
| Purity Grade | ≥98% (HPLC) | ≥97% | ≥99% |
| Pharmaceutical Compatibility | High | Moderate | Limited |
2. Industrial Applications & Functional Mechanisms
2.1 Pharmaceutical Intermediate
Enables synthesis of kinase inhibitors (e.g., JAK/STAT pathway modulators) through Suzuki-Miyaura cross-coupling reactions.
2.2 Agrochemical Precursor
Key component in systemic herbicides showing 94% weed suppression efficiency at 200g/ha concentration.
3. Operational Protocols & Safety Guidelines
| Parameter | Requirement |
|---|---|
| Storage Conditions | 2-8°C in amber glass under argon |
| Reaction Solvents | THF/DMF (anhydrous, oxygen-free) |
4. Case Studies: Real-World Implementations
4.1 Pharmaceutical: Kinase Inhibitor Development
Client: Top 10 Global Pharma Company
Result: 40% yield improvement in Buchwald-Hartwig amination steps
4.2 Electronics: OLED Material Synthesis
Client: Taiwan-based Display Manufacturer
Result: Achieved 15% luminance enhancement in blue-emitting layers
5. Procurement Strategy & Supplier Evaluation
5.1 Technical Specifications Checklist
- Batch-to-batch consistency: ≤0.3% variance
- Heavy metal content: <5ppm
5.2 Competitive Quotation Analysis
| Supplier | Price (USD/kg) | Lead Time |
|---|---|---|
| Vivalr Chemicals | $1,850 | 2-3 weeks |
Request Customized Quote
Contact our technical team for batch-specific analytical reports:
Email: info@vivalr.com
Tel: (86) 15866781826
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