2,6-Dichloropyridine-4-carboxaldehyde

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Table of Contents

  1. Product Overview & Specifications
  2. Detailed Applications
  3. Usage Case Studies
  4. Real Client Implementations
  5. Contact for Technical Consultation

1. Product Overview & Specifications

1.1 Key Parameters

Parameter Specification
CAS Number 102979-45-9
Molecular Formula C₆H₃Cl₂NO
Molecular Weight 192.00 g/mol
Appearance White to pale yellow crystalline powder
Purity ≥98% (HPLC)
Melting Point 98-102°C
Storage 2-8°C in airtight container

1.2 Comparative Analysis

Feature 2,6-Dichloro-4-carboxaldehyde Similar Derivatives
Reactivity High (dual Cl activation) Moderate
Solubility DCM, THF, DMF Limited in polar solvents
Synthetic Flexibility 3 reactive sites 1-2 reactive sites

2. Detailed Applications

2.1 Pharmaceutical Intermediate

Critical precursor for:

  • Kinase inhibitor development
  • Anticancer drug candidates
  • Neurological disorder treatments

2.2 Agrochemical Synthesis

Key component in:

  • Herbicide metabolites
  • Fungicide intermediates
  • Plant growth regulators

2.3 Material Science

  • Coordination polymer construction
  • Ligand synthesis for metal complexes
  • Photoactive material precursors

3. Usage Case Studies

3.1 Antiviral Drug Synthesis

Used in 7-step synthesis of protease inhibitors:

  • Conversion yield: 82% in Buchwald-Hartwig amination
  • Final API purity: 99.7%

3.2 Crop Protection Formulation

Central intermediate in systemic fungicide production:

  • 20% yield improvement vs. traditional routes
  • Reduced reaction temperature (60°C → 40°C)

4. Real Client Implementations

4.1 European Pharma Leader

  • Application: Oncology drug intermediate
  • Result: 30% cost reduction in lead optimization
  • Scale: 150kg/month production

4.2 Asian Agrochemical Producer

  • Usage: Novel herbicide development
  • Outcome: 6-month faster regulatory approval
  • Capacity: 3 metric tons/quarter

5. Contact for Technical Consultation

Request custom synthesis protocols or bulk pricing:

Technical support includes:

  • MSDS documentation
  • Process optimization guidance
  • Regulatory compliance assistance
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