CAS Number: 38275-57-9
Molecular Formula: C5H2BrN3
Molecular Weight: 184.99 g/mol
Synonyms: 5-Bromo-2-cyanopyrimidine, 2-Cyano-5-bromopyrimidine
Parameter | 5-Bromopyrimidine-2-carbonitrile | 5-Bromo-6-methyl-2-pyridinecarbonitrile |
---|---|---|
CAS Number | 38275-57-9 | 1173897-86-3 |
Molecular Weight | 184.99 | 197.03 |
Core Structure | Pyrimidine ring | Pyridine ring |
This brominated pyrimidine derivative serves as a critical intermediate in:
Used in multi-step synthesis of tyrosine kinase inhibitors targeting EGFR mutations.
Serves as a precursor in the creation of novel acetolactate synthase (ALS) inhibitors.
Application: Development of third-generation EGFR inhibitors
Result: Achieved 92% yield in Suzuki-Miyaura coupling reactions
Application: Synthesis of broad-spectrum herbicides
Result: Reduced production costs by 18% through optimized reaction pathways
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