5-Bromopyrimidine-2-carbonitrile: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
CAS Number: 38275-57-9
Molecular Formula: C5H2BrN3
Molecular Weight: 184.99 g/mol
Synonyms: 5-Bromo-2-cyanopyrimidine, 2-Cyano-5-bromopyrimidine
Comparative Analysis
| Parameter | 5-Bromopyrimidine-2-carbonitrile | 5-Bromo-6-methyl-2-pyridinecarbonitrile |
|---|---|---|
| CAS Number | 38275-57-9 | 1173897-86-3 |
| Molecular Weight | 184.99 | 197.03 |
| Core Structure | Pyrimidine ring | Pyridine ring |
2. Key Applications
This brominated pyrimidine derivative serves as a critical intermediate in:
- Pharmaceutical synthesis (e.g., kinase inhibitors)
- Agrochemical development (herbicide precursors)
- Material science research (coordination polymers)
- Organic electronics (semiconductor precursors)
3. Usage Scenarios
Scenario 1: Anticancer Drug Development
Used in multi-step synthesis of tyrosine kinase inhibitors targeting EGFR mutations.
Scenario 2: Herbicide Formulation
Serves as a precursor in the creation of novel acetolactate synthase (ALS) inhibitors.
4. Client Case Studies
Case Study 1: PharmaTech Solutions
Application: Development of third-generation EGFR inhibitors
Result: Achieved 92% yield in Suzuki-Miyaura coupling reactions
Case Study 2: AgroSolutions Ltd.
Application: Synthesis of broad-spectrum herbicides
Result: Reduced production costs by 18% through optimized reaction pathways
5. Contact for Technical Inquiries
Email: info@vivalr.com
Phone: (86) 15866781826
Request custom synthesis protocols or bulk pricing:
- GMP-grade production available
- Batch sizes from 100g to 100kg
- Technical documentation support


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