6-Amino-2-hydroxypyridine: Technical Guide & Applications
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 6-Amino-2-hydroxypyridine | Analogous Compounds |
|---|---|---|
| CAS Number | 5154-00-7 | 38767-72-5 (4-Amino-2-hydroxypyridine) 59315-44-5 (3-Amino-2-hydroxypyridine) |
| Molecular Formula | C5H6N2O | C5H6N2O (Isomeric variations) |
| Molecular Weight | 110.11 g/mol | 110.11 g/mol (Structural isomers) |
| Stability | Light-sensitive | Varies by substitution pattern |
2. Key Applications & Functional Properties
This heterocyclic compound serves critical roles in:
- Pharmaceutical Intermediates: Synthesis of bioactive molecules through regioselective reactions
- Coordination Chemistry: Ligand formation with transition metals for catalytic systems
- Agrochemical Development: Building block for pesticide metabolites
- Material Science: Precursor for conductive polymers and OLED components
3. Operational Guidelines & Best Practices
Storage: Maintain in amber glass at 2-8°C under inert atmosphere
Handling: Use nitrogen-purged reactors for amino-group protection reactions
Reactivity Profile:
- Participates in Buchwald-Hartwig amination
- Undergoes palladium-catalyzed cross-coupling
- pH-dependent solubility (pKa ~4.2)
4. Industry Case Studies
Case 1: Antiviral Drug Synthesis
Used as nucleoside analog precursor in HCV protease inhibitor development
Case 2: Metal-Organic Frameworks
Enabled creation of Cu(II)-based MOFs with 89% porosity enhancement
5. Client Success Stories
PharmaTech Solutions
Achieved 32% yield improvement in kinase inhibitor synthesis through optimized coupling protocols
Advanced Materials Co.
Developed corrosion-resistant coatings using nickel coordination complexes
6. Technical Consultation & Inquiry
For batch-specific COA, custom synthesis, or technical support:
Email: info@vivalr.com
Tel: (86) 15866781826
相关产品
Chemical Name: 3-Hydroxybutyric acid
CAS No.: 625-71-8
Molecular Formula: C4H8O3
Molecular Weight: 104.1
Appearance: White powder
Chemical Name: 4-((2-Furylmethyl)thio)-4-methylpentan-2-one
Cas No.: 64835-96-7
Molecular Fomula: C11H16O2S
Molecular Weight: 212.31
Appearance: Colorless to light yellow liquid
Chemical Name: 3-Hydroxybutyric acid
CAS No.: 625-71-8
Molecular Formula: C4H8O3
Molecular Weight: 104.1
Appearance: White powder
Chemical Name: Zinc citrate
Synonyms: Zinc citrate trihydrate
CAS No.: 546-46-3
Molecular Formula: C6H8O7Zn
Molecular Weight: 257.5
Appearance: White powder
Chemical Name: D-Phenothrin
CAS No.: 26046-85-5
Molecular Formula: C23H26O3
Molecular Weight: 350.45
Appearance: Oil
Chemical Name: Oxirane, methyl-, polymer with oxirane, dodecyl ether
Cas No.: 68238-81-3
Molecular Fomula: C17H36O3
Molecular Weight: 288.46594
Chemical Name: o-Xylene
Synonyms: 1,2-Dimethylbenzene; ortho-xylene
CAS No.: 95-47-6
Molecular Formula: C8H10
Molecular Weight: 106.17
Chemical Name: 1-Hexadecylamine
Synonyms 1-Aminohexadecane; Hexyldecylamine; n-Certylamine
CAS No.: 143-27-1
Molecular Formula: C16H35N
Molecular Weight: 241.46
Appearance: White Crystal
Chemical Name: 1-[9-ethyl-6-(4-fluoro-benzoyl)-9H-carbazol-3-yl]-ethanone
Cas No.: 876907-97-0
Molecular Fomula: C23H18FNO2
Molecular Weight: 359.39
Chemical Name: 1,5-Diphenylcarbazide
Synonyms: 1,5-Diphenylcarbohydrazide; 2,2’-diphenylcarbazide; Diphenylcartazide; sym-diphenylcarbazide
CAS No.: 140-22-7
Molecular Formula: C13H14N4O
Molecular Weight: 242.28
Chemical Name: Ammonium Iron(II) Sulfate
Synonyms: Diammonium iron bis(sulphate); iron (ii) ammonium sulfate
CAS No.: 10045-89-3
Molecular Formula: FeH5NO4S
Molecular Weight: 170.95
Chemical Name: DL-4-Chlorophenylglycine
Cas No.: 6212-33-5
Molecular Fomula: C8H8ClNO2
Molecular Weight: 185.61
评论
目前还没有评论。