2-Chloro-3-hydroxypyridine Technical Guide
Contents
- Product Overview & Specifications
- Comparative Parameter Analysis
- Industrial Applications
- Operational Case Studies
- Client Implementation Examples
- Technical Consultation
Product Overview & Specifications
| Parameter | Value |
|---|---|
| CAS No. | 6636-78-8 |
| Molecular Formula | C5H4ClNO |
| Molecular Weight | 129.54 g/mol |
| Appearance | Off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Melting Point | 167-172°C |
| Boiling Point | 316.2°C at 760 mmHg |
| Solubility | Partially soluble in cold water, fully soluble in hot water |
| Storage | Maintain at 2-8°C in airtight container |
Comparative Parameter Analysis
| Grade | Pharmaceutical | Industrial |
|---|---|---|
| Purity | ≥99.5% | ≥98% |
| Heavy Metals | <5 ppm | <20 ppm |
| Residual Solvents | USP Class 2 Compliant | Standard Grade |
| Certifications | GMP, DMF Filed | Technical Grade |
Industrial Applications
Pharmaceutical Intermediate: Key precursor for antiretroviral agents and kinase inhibitors
Agrochemical Synthesis: Building block for novel neonicotinoid insecticides
Coordination Chemistry: Chelating agent for transition metal catalysts
Material Science: Monomer for conductive polymer development
Operational Case Studies
Case 1: Optimized coupling reaction with Grignard reagents (Yield improvement: 62% → 89%)
Case 2: Scale-up production achieving 98.7% purity through recrystallization
Case 3: Cross-coupling reactions in flow chemistry systems (Throughput: 15 kg/day)
Client Implementation Examples
Client A: European API Manufacturer
– Application: HCV protease inhibitor intermediate
– Annual Consumption: 850kg
– Technical Support: Custom particle size distribution optimization
Client B: Asian Crop Science Leader
– Application: Systemic insecticide development
– Implementation: Continuous process development
– Outcome: 40% reduction in synthetic steps
Technical Consultation
For material specifications, custom synthesis, or technical documentation:
Email: info@vivalr.com
Tel: (86) 15866781826
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