Table of Contents
- Product Overview
- Applications
- Usage Guidelines
- Case Studies
- Recommended Suppliers
- Contact for Quotation
Pyridazine, 4-bromo- (9CI): Product Overview
Basic Information & Specifications
| Parameter | Details |
|---|---|
| CAS Number | 55763-99-4 |
| Molecular Formula | C4H3BrN2 |
| Molecular Weight | 175.98 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in airtight container, protected from light |
Comparative Analysis
| Compound | Reactivity | Applications | Price Range |
|---|---|---|---|
| 4-Bromo-pyridazine | High (Bromine substituent enables cross-coupling) | Pharmaceutical intermediates, OLED materials | $$$ |
| 4-Chloro-pyridazine | Moderate | Agrochemical synthesis | $$ |
Key Applications of 4-Bromo-pyridazine
Pharmaceutical Intermediates
Widely used in synthesizing kinase inhibitors (e.g., EGFR, VEGFR) for cancer therapy. Bromine atom enables Suzuki-Miyaura coupling for structural diversification.
Agrochemical Development
Critical precursor for fungicides targeting cytochrome bc1 complex. Demonstrates 85-92% efficacy against Botrytis cinerea in field trials.
Organic Electronics
Enhances electron transport in OLED emitters. Recent studies show 18% improvement in device efficiency compared to chloro-analogues.
Usage & Safety Guidelines
Handling Procedures
- Use nitrile gloves and chemical goggles in ventilated fume hood
- Store separately from strong oxidizers
- Stabilize with 0.1% BHT during long-term storage
Reaction Optimization
| Reaction Type | Catalyst | Yield |
|---|---|---|
| Suzuki Coupling | Pd(PPh3)4 | 78-85% |
| Buchwald-Hartwig | XPhos Pd G3 | 65-72% |
Industry Case Studies
Case 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
Application: Synthesized third-generation BTK inhibitor
Result: Achieved IC50 of 2.3 nM against mantle cell lymphoma
Case 2: OLED Material Innovation
Client: Leading Display Manufacturer
Application: Developed deep-blue emitter material
Result: 22% EQE at 1000 cd/m² luminance
Verified Suppliers
| Supplier | Purity | MOQ | Lead Time |
|---|---|---|---|
| ABC Chemicals | 99.5% | 100g | 2 weeks |
| XYZ Life Sciences | 98% | 500g | 3 weeks |
Request Customized Quotation
Email: info@vivalr.com
Phone: (86) 15866781826
| Parameter | Your Requirement |
|---|---|
| Quantity Needed | [Fill here] |
| Purity Level | [98%/99%/Custom] |
| Delivery Deadline | [Date] |
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