3-Bromo-2,6-dimethylpyridine

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3-Bromo-2,6-dimethylpyridine User Guide

1. Product Overview & Specifications

3-Bromo-2,6-dimethylpyridine (CAS 52334-83-3) is a brominated pyridine derivative widely used in pharmaceutical synthesis and organic intermediates. Key parameters:

Parameter Value
Molecular Formula C7H8BrN
Molecular Weight 190.05 g/mol
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder

Comparative Analysis

Compound Molecular Weight Melting Point Solubility
3-Bromo-2,6-dimethylpyridine 190.05 42-45°C Soluble in DCM, Ethanol
2-Bromo-5-methylpyridine 172.01 38-41°C Soluble in THF

2. Key Applications

  • Pharmaceutical Intermediates: Critical in synthesizing kinase inhibitors and antiviral agents.
  • Catalyst Ligands: Facilitates cross-coupling reactions (e.g., Suzuki-Miyaura).
  • Agrochemicals: Building block for herbicides and fungicides.

3. Usage Scenarios

Scenario 1: Drug Synthesis

Used in a 3-step synthesis of a tyrosine kinase inhibitor, achieving 89% yield under palladium catalysis.

Scenario 2: Material Science

Incorporated into OLED emissive layers to enhance electron transport efficiency by 22%.

4. Client Case Studies

Case 1: PharmaTech Inc.

Application: Synthesis of preclinical antiviral compound
Result: Reduced reaction time by 35% compared to alternative bromopyridines.

Case 2: ChemCatalyst Co.

Application: Ligand in asymmetric hydrogenation
Result: Achieved 92% enantiomeric excess (ee) in chiral amine production.

5. Request a Quote

Contact our technical team for bulk pricing, SDS, or custom synthesis inquiries:

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