2-Fluoropyridine: Comprehensive Technical Guide
Table of Contents
1. Basic Information & Specifications
| Parameter | Specification | Comparative Analysis |
|---|---|---|
| CAS Number | 372-48-5 | Unique identifier vs. similar fluoropyridines |
| Molecular Formula | C5H4FN | Simpler structure than bromo-fluoropyridine derivatives |
| Molecular Weight | 97.09 g/mol | Lower molecular weight vs. iodinated analogs |
| Boiling Point | 126°C | Higher volatility than 5-bromo-2-fluoropyridine (162-164°C) |
| Refractive Index | n20/D 1.46 | Standard optical characteristics for pyridine derivatives |
2. Key Applications
- Pharmaceutical Intermediates: Core building block for antiviral and anticancer agents
- Agrochemical Synthesis: Precursor for advanced crop protection chemicals
- Organic Electronics: Electron-deficient component in OLED materials
- Coordination Chemistry: Ligand precursor for transition metal complexes
3. Industry Applications
Case Study 1: Antiviral Drug Development
Used as key intermediate in synthesis of neuraminidase inhibitors through Suzuki-Miyaura cross-coupling reactions.
Case Study 2: Liquid Crystal Formulations
Employed as polar component in nematic liquid crystal mixtures for display technologies (5-10% w/w formulations).
4. Safety & Handling
| Parameter | Requirement |
|---|---|
| Storage Temperature | 2-8°C under inert atmosphere |
| Flash Point | 24°C (CC) – Flammable liquid |
| Personal Protection | Neoprene gloves + full-face respirator |
5. Certified Suppliers
| Supplier | Purity | Packaging |
|---|---|---|
| Hubei Zhenbo Chemical | ≥99% | 25kg drums |
| Seebio Biotech (Shanghai) | ≥98.5% | 1kg/5kg glass bottles |
6. Technical Inquiry
For analytical certificates, bulk pricing, or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
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