Methyl 3-amino-6-bromopyrazine-2-carboxylate: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chemical Properties
Methyl 3-amino-6-bromopyrazine-2-carboxylate (CAS: 1261586-65-3) is a brominated pyrazine derivative with molecular formula C6H6BrN3O2 and molecular weight 248.04 g/mol. This yellow crystalline powder is soluble in DMSO and methanol.
Parameter Comparison
| Parameter | Supplier A | Supplier B | Our Product |
|---|---|---|---|
| Purity | ≥97% | ≥98% | ≥99% (HPLC) |
| Packaging | 1g-100g | 5g-500g | 1g-5kg |
| Price (per gram) | $85 | $78 | $72 |
2. Key Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesizing antiviral agents (e.g., HCV protease inhibitors) and kinase inhibitors for cancer therapy. The bromine atom enables efficient Suzuki couplings for structural diversification.
Material Science
Employed as building blocks for organic semiconductors and photoactive materials in OLED development. Amino and ester groups allow post-functionalization for tailored electronic properties.
3. Industrial Case Studies
Case 1: PharmaTech Innovations
Application: Synthesis of novel PI3K/mTOR dual inhibitors
Result: Achieved 92% yield in Buchwald-Hartwig amination step, reducing production costs by 18% versus previous intermediates.
Case 2: Global BioMed Solutions
Application: Development of broad-spectrum antiviral compounds
Result: Enabled creation of lead compound with EC50 = 3.2 nM against SARS-CoV-2, currently in preclinical trials.
4. Technical Support & Inquiries
Our technical team provides:
- Custom synthesis up to kilogram-scale
- HPLC/GCMS analytical reports
- Regulatory documentation support
Contact our specialists for project-specific solutions:
Email: info@vivalr.com
Tel: (86) 15866781826
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