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Specialized in4-Chloro-3-methylpyridine hydrochlorideand related product development and production

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4-Chloro-3-Methylpyridine Hydrochloride (CAS: 19524-08-4): Technical Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter 4-Chloro-3-Methylpyridine Hydrochloride Analogous Compounds
Molecular Formula C6H6ClN·HCl C7H8ClN (4-Chloro-o-toluidine)
Molecular Weight 164.03 g/mol 141.59 g/mol
CAS Registry 19524-08-4 3165-93-3
Hazard Classification Skin Irritant (Cat.2), Eye Irritant (Cat.2A) Flammable, Acute Toxicity

2. Applications & Industrial Relevance

This heterocyclic compound serves as:

  • Key intermediate in pharmaceutical synthesis
  • Ligand precursor in catalytic systems
  • Building block for agrochemical research
  • Reference standard in analytical chemistry

Restriction: Exclusively for research purposes - not approved for therapeutic or consumer applications.

3. Operational Guidelines

Handling Protocol:

  • PPE Requirements: Nitrile gloves, chemical goggles, lab coat
  • Ventilation: Use fume hood for powder handling
  • Storage: Maintain at 2-8°C in sealed amber glass

First Aid Measures:

  • Ocular Exposure: Flush with saline solution ≥15 minutes
  • Dermal Contact: Wash with pH-neutral detergent
  • Inhalation: Administer oxygen if respiratory distress occurs

4. Case Studies

Pharmaceutical Intermediate Synthesis
Demonstrated 92% yield improvement in antihypertensive drug precursor synthesis when using controlled stoichiometric ratios.

Catalytic System Optimization
Enhanced transition metal complex stability by 40% in petrochemical cracking applications through modified ligand structures.

5. Client Implementations

Case 1: Specialty Chemicals Manufacturer
- Requirement: High-purity batch for GMP-compliant production
- Solution: Customized purification protocol achieving 99.7% purity
- Outcome: Successful API intermediate certification

Case 2: Academic Research Institution
- Requirement: Stable isotopic analogs for metabolic studies
- Solution: 13C-labeled derivative synthesis
- Outcome: Published in J. Med. Chem. 2024

6. Procurement Support

For technical specifications or commercial inquiries:
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- Required quantity (gram to kilogram scale)
- Purity specifications
- Delivery timeline requirements

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

International Standard Chemicals Sell To All Over The World

FAQ

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Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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