Parameter | Specification | Comparison Compound |
---|---|---|
CAS Number | 34404-67-0 | Pyridine N-oxide (704-32-3) |
Molecular Formula | C5H5NO2 | Pyridine (C5H5N) |
Purity Grade | ≥99% (HPLC) | Industrial grade (95-98%) |
Melting Point | 128-131°C | Pyridine: -41.6°C |
Solubility | Water: 50g/L (20°C) | Pyridine: Miscible |
2-Pyridinol-1-oxide demonstrates superior thermal stability (decomposition >250°C) and pH tolerance (stable in pH 3-10 solutions), making it ideal for:
Critical component in synthesis of:
Key functionality in:
Challenge: Improve yield in nitrofurantoin precursor synthesis
Solution: Implemented 2-Pyridinol-1-oxide as coordinating agent
Result: 22% yield increase with 15% reduction in side products
Challenge: Develop pH-stable fungicide for tropical climates
Solution: Utilized thermal stability properties
Result: 18-month shelf life at 40°C/75% RH conditions
Application: Antibacterial drug synthesis
Usage: 850kg/month production scale
Outcome: Achieved 99.7% API purity (ICH Q3D compliant)
Application: Systemic fungicide production
Usage: 12MT annual consumption
Outcome: 92% disease suppression rate in field trials
Application: Neurological drug development
Usage: 50kg pilot batch quantities
Outcome: Successful Phase I clinical trial material preparation
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