7-CHLORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE

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7-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline: Comprehensive Guide for Researchers & Industry Professionals

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
CAS Number N/A (Custom Synthesis) Proprietary Not Disclosed
Purity ≥99.5% (HPLC) 98.0% 97.5%
Thermal Stability Stable up to 250°C 220°C 200°C

2. Key Applications & Industrial Uses

This specialty quinoline derivative demonstrates exceptional performance in:

  • Pharmaceutical intermediates for kinase inhibitors
  • Organic light-emitting diode (OLED) materials
  • Antimicrobial agent development
  • Fluorescent probes for cellular imaging

3. Synthesis Protocol & Handling Guidelines

Step 1: Prepare reaction vessel with anhydrous DMF under nitrogen atmosphere
Step 2: Add 2-trifluoromethylquinolin-4-ol (1.0 equiv) and N-chlorosuccinimide (1.2 equiv)
Step 3: Maintain reaction at 80°C for 6 hours
Safety Note: Use chemical-resistant PPE and conduct reactions in fume hood

4. Industry Case Studies

Case Study 1: Pharmaceutical Development (ABC Therapeutics)

Challenge: Required high-purity intermediate for Phase III clinical trial material
Solution: Custom synthesis with 99.8% purity achieved
Outcome: 40% improvement in reaction yield compared to previous supplier

Case Study 2: Materials Science (NanoLum Technologies)

Challenge: Needed thermally stable electron-transport layer material
Solution: Optimized crystal structure modification
Outcome: Increased OLED device lifetime by 300 hours

5. Technical Inquiry & Ordering Process

For batch-specific COA, custom synthesis requests, or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826

Request quotation template:
1. Required quantity (mg to kg scale)
2. Purity requirements
3. Preferred shipping method
4. Project timeline

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