Directory
- Product Overview
- Specifications & Comparative Analysis
- Applications
- Usage Cases
- Client Case Studies
- Contact for Quotation
4-Amino-3,5-dichloro-2,6-difluoropyridine Overview
Basic Information
| CAS Number | 72680-25-6 |
|---|---|
| Molecular Formula | C5H2Cl2F2N2 |
| Molecular Weight | 217.98 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in airtight container |
Comparative Analysis with Similar Compounds
| Parameter | 4-Amino-3,5-dichloro-2,6-difluoropyridine | 2-Chloro-5-fluoropyridine | 3,5-Dichloropyridine |
|---|---|---|---|
| Reactivity | High (multiple halogen sites) | Moderate | Low |
| Pharmaceutical Utility | Broad-spectrum intermediate | Limited API use | Niche applications |
| Thermal Stability | Stable up to 200°C | Decomposes at 150°C | Stable up to 180°C |
Key Applications
Pharmaceutical Intermediates
Used in synthesis of antiviral agents and kinase inhibitors due to its ability to facilitate nucleophilic substitution reactions at Cl/F sites.
Agrochemicals
Critical component in next-gen herbicides targeting acetyl-CoA carboxylase (ACCase) enzymes in weeds.
Material Science
Serves as building block for liquid crystal polymers (LCPs) in 5G-capable electronic components.
Industry-Specific Usage Scenarios
Case 1: Antiviral Drug Development
In COVID-19 therapeutic research, this compound enabled precise modification of RNA polymerase inhibitors’ binding affinity through selective halogen interactions.
Case 2: Precision Herbicides
Agrochem leader Syngenta® utilized it to develop temperature-stable pre-emergent herbicides with 40% lower environmental persistence than traditional chloroacetanilides.
Verified Client Implementations
Client A: Top 10 Pharma Company (Confidential)
- Project: Synthesis of broad-spectrum antiviral candidate
- Result: Achieved 92% yield in Buchwald-Hartwig amination step
- Volume: 150kg/year under cGMP
Client B: European Agrochemical Innovator
- Application: Non-selective herbicide for GM crop systems
- Outcome: Reduced application frequency by 33% in field trials
- Regulatory: Successfully passed OECD 301F biodegradability testing
Request Customized Quotation
Contact our technical sales team for batch-specific pricing, regulatory documentation, and synthesis scale-up support:
Email: info@vivalr.com
Tel: (86) 15866781826


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