4,5-Dichloro-3(2H)-pyridazinone

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4,5-Dichloro-3(2H)-Pyridazinone: Technical Guide for Industrial Applications

1. Product Specifications & Comparative Analysis

Parameter 4,5-Dichloro-3(2H)-Pyridazinone Similar Derivatives
CAS Number 932-22-9 26806-47-3, 933-76-6
Molecular Formula C4H2Cl2N2O C11H5Cl2F3N2O (Derivative)
Molecular Weight 177.0 g/mol 179.0–309.1 g/mol
Purity ≥98% 98% (HPLC)
Storage RT, dry environment RT, sealed containers

Key Advantage: Superior stability under ambient conditions compared to fluorinated derivatives (e.g., 26806-47-3).

2. Industrial Applications

Core Use Cases:

  • Agrochemical Synthesis: Intermediate for herbicides (e.g., Norflurazon analogs) and fungicides.
  • Pharmaceuticals: Building block for anti-inflammatory agents (e.g., Emorfazone intermediates).
  • Electronics: Precursor in specialty polymer production.

Performance Advantages:

  • High reactivity in nucleophilic substitution reactions
  • Thermal stability up to 200°C

3. Operational Protocols

Recommended Workflow:

  1. Handle in controlled environments (humidity <40%)
  2. Use anhydrous solvents for optimal reaction yields
  3. Maintain pH 6–8 in aqueous systems

Safety Profile:

  • LD50 (oral, rat): 1,250 mg/kg
  • Non-flammable but requires PPE during handling

4. Client Success Stories

Case 1: Agrochemical Producer (Shanghai)

  • Challenge: Needed cost-effective herbicide intermediate
  • Solution: Custom synthesis at 99% purity
  • Outcome: 30% production cost reduction

Case 2: Pharmaceutical Developer (Zhejiang)

  • Challenge: Required GMP-grade intermediate
  • Solution: Batch optimization for ICH stability standards
  • Outcome: Successful FDA pre-approval inspection

5. Request Customized Solutions

Optimize your production with our technical expertise:

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