1,5-NAPHTHYRIDINE: Comprehensive Product Guide
Table of Contents
1. Product Specifications & Comparison
| Parameter | 1,5-Naphthyridine | 4-Chloro-1,5-Naphthyridine | 8-Chloro-2-Methoxy-1,5-Naphthyridine |
|---|---|---|---|
| CAS No. | 254-79-5 | N/A | 249889-68-7 |
| Molecular Formula | C8H6N2 | C8H5ClN2 | C9H7ClN2O |
| Molecular Weight | 130.15 g/mol | 164.60 g/mol | 194.62 g/mol |
| Boiling Point | 248.9°C | N/A | N/A |
| Density | 1.183 g/cm³ | N/A | N/A |
| HS Code | 29339900.90 | ||
Safety: S26; S36/37/39; S39 (Wear gloves/eye protection in ventilated areas).
2. Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesizing antibiotics, antiviral agents, and kinase inhibitors (e.g., SB-334867). Its nitrogen-rich structure enables precise molecular modifications for drug candidates.
Fluorescent Dyes
Serves as a backbone for bivinyl naphthyridine fluorescent dyes in bioimaging and diagnostic assays due to its stable luminescent properties.
Agrochemical Research
Key precursor in developing plant growth regulators and pesticide intermediates, leveraging its heterocyclic reactivity.
3. Client Success Stories
Case 1: Shanghai Macklin Biochemical Co., Ltd.
Application: Synthesis of 8-Chloro-2-Methoxy-1,5-Naphthyridine (CAS 249889-68-7) for oncology drug research.
Outcome: Achieved 98% purity for preclinical trials, reducing synthesis steps by 30%.
Case 2: Yuhan Chemical Co., Ltd.
Application: Bulk production of 1,5-Naphthyridine as a core intermediate for antibacterial agents.
Outcome: Scalable manufacturing with ≤0.5% impurity, compliant with ISO 9001 standards.
4. Technical Inquiries
For pricing, custom synthesis, or regulatory documentation:
| info@vivalr.com | |
| Phone | (86) 15866781826 |
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