6-Iodoquinoline

Comprehensive Guide to 6-Iodoquinoline: Applications, Case Studies, and Supplier Insights

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications of 6-Iodoquinoline
• 3. Comparative Analysis with Similar Compounds
• 4. Step-by-Step Usage Guidelines
• 5. Real-World Case Studies
• 6. Request a Quote or Sample

1. Product Overview & Specifications

6-Iodoquinoline (CAS 13138-25-5) is a halogenated quinoline derivative widely used in pharmaceuticals, agrochemicals, and organic synthesis. Key specifications include:

2. Key Applications of 6-Iodoquinoline

2.1 Pharmaceutical Intermediates

Used in synthesis of antimalarial and anticancer agents due to its bioisosteric properties.

2.2 Catalytic Cross-Coupling Reactions

Acts as a key substrate in Buchwald-Hartwig amination and Suzuki-Miyaura reactions.

3. Comparative Analysis with Similar Compounds

4. Step-by-Step Usage Guidelines

4.1 Handling Precautions

Use nitrile gloves and eye protection; avoid inhalation of dust.

4.2 Reaction Setup Example

For Suzuki coupling: Mix 1eq 6-iodoquinoline with 1.2eq boronic acid in degassed DME under N₂.

5. Real-World Case Studies

5.1 Case Study: Antiviral Drug Development

Client: European Pharma Company
Challenge: Synthesize novel HCV protease inhibitor
Solution: Used 6-iodoquinoline in Pd-mediated cross-coupling (92% yield)
Outcome: Accelerated preclinical development by 6 months

5.2 Case Study: OLED Material Research

Client: Asian Tech University
Challenge: Develop thermally stable electron transport layer
Solution: Incorporated 6-iodoquinoline into coordination polymer
Outcome: Achieved 15% improvement in device lifetime

6. Request a Quote or Sample

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