2-Methoxypyrimidine-5-boronic Acid: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2-Methoxypyrimidine-5-boronic Acid (CAS 1072833-48-1) is a high-purity boronic acid derivative widely used in Suzuki-Miyaura cross-coupling reactions. Key specifications include:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥98% | ≥95% | ≥97% |
| Molecular Formula | C5H7BN2O3 | – | – |
| Storage | 2-8°C, dry | Ambient | 2-8°C |
2. Key Applications
- Pharmaceutical Synthesis: Critical intermediate for kinase inhibitors and antiviral agents.
- Agrochemicals: Building block for fungicide development.
- Material Science: Used in OLED precursor synthesis.
3. Usage Scenarios
Scenario 1: API Intermediate Production
Used in a 3-step synthesis of Abemaciclib (CDK4/6 inhibitor) with 82% overall yield under inert conditions.
Scenario 2: Cross-Coupling Optimization
Demonstrated 95% conversion rate in Pd-catalyzed reactions at 80°C with 1.5 eq. base.
4. Customer Case Studies
Case 1: Top 10 Pharma Company (2023)
Scaled production of oncology drug candidates using our boronic acid reduced impurity levels by 40% vs. previous suppliers.
Case 2: Specialty Chemical Manufacturer
Achieved 30% cost savings in agrochemical R&D through improved reaction efficiency.
5. Request a Quote
Optimize your synthesis workflows with premium-grade 2-Methoxypyrimidine-5-boronic acid. Contact our technical team:
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