Chemical Name: 1,2-dioleoyl-sn-glycero-3-phosphate sodium salt
CAS No.: 108392-02-5
Molecular Fomula: C39H74NaO8P
Molecular weight: 724.98
Appearance: White to light yellow powder
Parameter | Specification | Competitor A | Competitor B |
---|---|---|---|
CAS Number | 108392-02-5 | 108392-02-5 | 108392-02-5 |
Molecular Formula | C39H74NaO8P | Same | Same |
Molecular Weight | 724.98 g/mol | 724.98 | 724.98 |
Purity | ≥99% | 98.5% | 99.44% |
Packaging | 25mg, 50mg | 5mg, 10mg | 10mM*1mL |
Application | Protocol | Performance Metrics |
---|---|---|
Liposome Preparation | Thin-film hydration method | ≥85% encapsulation efficiency |
Membrane Protein Studies | Surface plasmon resonance | KD values 10-6-10-9 M |
Challenge: Required stable anionic liposomes for gene delivery
Solution: Optimized 18:1 PA/cholesterol ratio (7:3)
Outcome: Achieved 92% transfection efficiency in HEK293 cells
Challenge: Needed pH-responsive drug carriers
Solution: Developed DOPA-based nanoparticles
Result: 3X tumor accumulation vs conventional formulations
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