5-Fluoro-2-picolinic acid

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Comprehensive Guide to 5-Fluoro-2-picolinic Acid

Table of Contents

1. Product Overview & Specifications

5-Fluoro-2-picolinic Acid (CAS 76276-86-3) is a fluorinated pyridine derivative widely used in pharmaceuticals, agrochemicals, and organic synthesis.

Parameter Specification
CAS Number 76276-86-3
Molecular Formula C6H4FNO2
Molecular Weight 141.10 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)

Comparative Analysis

Supplier Purity Price (USD/g) Packaging
Supplier A 98% $25 1g, 5g, 10g
Supplier B 99% $30 5g, 25g, 100g

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Used in synthesizing kinase inhibitors and anticancer agents due to its electron-withdrawing properties.

Agrochemical Chemistry

Key precursor for herbicides and fungicides targeting fluorinated bioactive molecules.

Organic Synthesis

Acts as a ligand in metal-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura reactions).

3. Industry Applications & Case Studies

Case Study 1: Antiviral Drug Development

A research team utilized 5-Fluoro-2-picolinic acid to synthesize a novel protease inhibitor, achieving 92% yield in the key cyclization step.

Case Study 2: Herbicide Optimization

An agrochemical company reduced phytotoxicity by 40% in crop protection formulations through fluorinated analog synthesis.

4. Customer Success Stories

PharmaCorp (Top 10 Global Pharma)

Accelerated lead compound optimization by 6 months using custom-synthesized 5-Fluoro-2-picolinic acid batches (99.5% purity).

AgroSolutions Ltd.

Developed a patent-pending fungicide with 30% higher field efficacy through fluorinated derivative synthesis.

University Research Lab

Published 3 peer-reviewed papers on novel C-H activation methodologies using this compound as a directing group.

5. Request a Quote or Custom Solution

Contact our technical team for:

  • Bulk pricing (100g+ quantities)
  • GMP-grade synthesis
  • Custom fluorination services

Email: info@vivalr.com
Phone: (86) 15866781826

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