5-Bromo-2-fluoropyridine

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5-Bromo-2-fluoropyridine Ultimate Buyer’s Guide

Contents

Product Specifications & Comparative Analysis

Parameter 5-Bromo-2-fluoropyridine Similar Compounds
CAS Number 374-69-0 N/A
Molecular Formula C5H3BrFN C5H4FN (2-fluoropyridine)
Purity Grade ≥99% (HPLC) 97-98% typical
Storage Conditions 2-8°C in inert gas Room temperature

Applications & Industrial Usage

5-Bromo-2-fluoropyridine serves as critical building block in:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical synthesis (crop protection agents)
  • Ligand preparation in catalytic systems
  • Fluorinated liquid crystal materials

Operational Guidelines

Handling protocols:

Process Stage Requirements
Synthesis Use dry reaction vessels under N₂ atmosphere
Purification Column chromatography (silica gel, hexane/EA)
Quality Control GC-MS analysis, NMR verification

Case Studies

Case 1: API Development for NSCLC Treatment
Client: Top 10 Pharma Company
Application: Third-generation EGFR inhibitor synthesis
Outcome: Achieved 92% yield in key coupling reaction

Client Success Stories

Client A: European CRO
Project Scope: 15kg batch production
Technical Highlights:
– Consistent ≥99.5% purity across batches
– Reduced metal impurities to <10ppm
Delivery: 3 weeks from PO to shipment

Client B: US Electronic Materials Supplier
Application: Fluorinated semiconductor precursors
Customization:
– Particle size control (50-70μm)
– Special moisture-proof packaging
Results: 40% efficiency improvement in deposition process

Request Custom Quote

Contact our technical team for:

  • Bulk pricing (100kg+ orders)
  • Custom synthesis parameters
  • Regulatory support documentation

Direct Contacts:
Email: info@vivalr.com
Phone: (86) 15866781826

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