1. Product Overview & Specifications

2-Bromo-4-ethylpyridine (CAS 40248-27-3) is a brominated pyridine derivative widely used in pharmaceutical, agrochemical, and material science research. Key specifications include:

Comparative Analysis

2. Applications of 2-Bromo-4-ethylpyridine

Pharmaceutical Intermediates

Used in Suzuki-Miyaura cross-coupling reactions to synthesize kinase inhibitors and antiviral agents.

Agrochemical Synthesis

Key building block for herbicides and fungicides targeting crop protection.

Coordination Chemistry

Acts as a ligand in transition metal catalysts for asymmetric catalysis.

3. Usage Guidelines & Best Practices

Handling Precautions

• Use PPE: gloves, goggles, and lab coats.
• Avoid inhalation; work in fume hoods.

Reaction Optimization

Typical conditions: 1.5 eq. compound, Pd(PPh₃)₄ catalyst, 80°C in THF/water.

4. Case Studies

Case 1: Anticancer Drug Intermediate

A research team achieved 92% yield in synthesizing a Bruton’s tyrosine kinase (BTK) inhibitor using this compound.

Case 2: Herbicide Development

Enhanced selectivity in a glyphosate derivative synthesis, reducing byproducts by 40%.

5. Client Success Stories

Client A: Top-10 Pharma Company

Challenge: Low yield in EGFR inhibitor synthesis.
Solution: Optimized coupling reaction with 2-Bromo-4-ethylpyridine.
Result: Yield increased from 65% to 88%, accelerating preclinical trials.

Client B: Agrochemical Manufacturer

Challenge: Unstable intermediates in fungicide production.
Solution: Implemented bromopyridine-based pathway.
Result: 30% cost reduction and improved shelf-life stability.

6. Contact for Quotations

Request bulk pricing or technical support:

Email: info@vivalr.com
Phone: (86) 15866781826

Custom synthesis and COA/MSDS available upon request.