3-Chloro-2-nitropyridine

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3-Chloro-2-nitropyridine: Comprehensive Product Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter 3-Chloro-2-nitropyridine 2-Chloro-3-nitropyridine
CAS Number 54231-36-6 54727-18-3
Molecular Formula C5H3ClN2O2 C5H3ClN2O2
Purity ≥98% (HPLC) ≥97%
Thermal Stability Stable below 200°C Decomposes at 180°C

2. Industrial Applications & Functional Mechanisms

This heterocyclic compound demonstrates exceptional versatility in:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical precursors for neonicotinoid derivatives
  • Coordination chemistry in catalytic systems
  • Electrophilic substitution reactions

3. Application Scenarios in Synthetic Chemistry

3.1 Suzuki-Miyaura Cross-Coupling

Enables efficient biaryl synthesis under palladium catalysis (yield: 82-89%)

3.2 Nucleophilic Aromatic Substitution

Facilitates amine introduction at chloro position (reaction time: 4-6h at 80°C)

4. Verified Client Implementations

Case Study 1: Anticancer Drug Development

Client: Shanghai PharmaTech Co., Ltd. (GMP Certified)
Application: Key intermediate in third-generation EGFR inhibitors
Scale: 150kg/month production

Case Study 2: Advanced Herbicide Formulation

Client: AgriSolutions GmbH
Application: Core structure in systemic herbicides
Result: 40% improvement in weed control efficacy

5. Technical Consultation & Quotation

Request custom synthesis protocols or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Our advantages:

  • ISO 9001-certified production
  • 15-day lead time for 100kg+ orders
  • Customizable particle size distribution
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