3-Bromo-2-Hydroxy-5-Methylpyridine: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Bromo-2-Hydroxy-5-Methylpyridine |
| CAS Number | 1072-97-5 |
| Molecular Formula | C6H6BrNO |
| Molecular Weight | 188.02 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥99.0% |
| Storage Conditions | 2-8°C in airtight container |
2. Key Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesis of kinase inhibitors and antiviral agents. The bromine substituent enables efficient cross-coupling reactions for drug candidate diversification.
Agrochemical Development
Essential precursor for novel fungicides and herbicides, particularly effective in creating compounds with enhanced bioactivity and environmental stability.
Material Science
Building block for metal-organic frameworks (MOFs) and coordination polymers with potential applications in catalysis and gas storage.
3. Comparative Analysis
| Feature | 3-Bromo-2-Hydroxy-5-Methylpyridine | Similar Compound A | Similar Compound B |
|---|---|---|---|
| Reactivity in Suzuki Coupling | High (k = 0.45 min-1) | Moderate (k = 0.28 min-1) | Low (k = 0.12 min-1) |
| Thermal Stability | Stable up to 250°C | Decomposes at 180°C | Stable up to 200°C |
| Aqueous Solubility | 1.2 mg/mL (25°C) | 0.8 mg/mL | 2.1 mg/mL |
4. Implementation Scenarios
Anticancer Drug Synthesis
Step 1: Palladium-catalyzed cross-coupling with boronic acids
Step 2: Selective hydroxyl protection
Step 3: Final API purification
Crop Protection Formulation
Used in three-step synthesis of next-generation fungicides showing 92% efficacy against Phytophthora infestans in field trials.
5. Client Success Stories
Case 1: Top 10 Pharma Company
Challenge: Required high-purity intermediate for Phase III oncology drug
Solution: Custom synthesis with >99.5% purity
Result: 30% faster regulatory approval process
Case 2: Agrochemical Innovator
Challenge: Develop cost-effective fungicide with reduced environmental impact
Solution: Optimized 4-step synthesis route using our compound
Result: Achieved 40% production cost reduction vs traditional methods
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ quantities)
- Custom synthesis protocols
- Regulatory support documentation
Email: info@vivalr.com
Phone: (86) 15866781826
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