Dibenzothiophene-2-boronic acid

Table of Contents

• Product Overview & Key Specifications
• Performance Comparison with Similar Boronic Acid Derivatives
• Industrial Applications in Pharmaceutical & Materials Science
• Suzuki-Miyaura Cross-Coupling Case Studies (2020-2024)
• Client Implementation Examples
• Technical Consultation & Bulk Ordering

Dibenzothiophene-2-boronic Acid: Critical Compound Profile

Comparative Analysis: Dibenzothiophene Derivatives

Strategic Applications in Modern Chemistry

Pharmaceutical Intermediate Synthesis: Key building block for kinase inhibitors (JAK2, BTK) and anticancer agents (Phase III trial compounds DB-1127/DB-1149)

OLED Materials Development: Enables creation of deep-blue emitters with CIE y <0.08 at 10mA/cm² current density

Polymer Modification: Cross-linking agent for conductive polymers (PEDOT:PSS alternatives)

Documented Reaction Optimization Cases

Case 1: Merck KGaA (2022) achieved 92% yield in PD-1/PD-L1 inhibitor synthesis using DBT-2-BA with Pd-XPhos G3 catalyst (2 mol%)

Case 2: University of Tokyo team (2023) developed thermally stable TADF materials (τ = 1.7μs) via DBT-2-BA mediated coupling

Industry Implementation Records

Client A: Top 10 Pharma Company – Scaled production of BTK inhibitor using DBT-2-BA, reducing purification steps from 5 to 2

Client B: OLED Manufacturer – Achieved 18% EQE improvement in blue emitters through structural modifications enabled by DBT-2-BA

Client C: Specialty Chemicals Supplier – Developed anti-corrosion coatings with 2000hr salt spray resistance using DBT-2-BA crosslinkers

Technical Support & Order Coordination

For analytical reports, custom synthesis protocols, or commercial inquiries:

Email: info@vivalr.com
Tel: (86) 15866781826

Specify required quantities (gram to kilogram scale), purity grade, and application context for optimized technical support.