N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine

N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine: Comprehensive Product Guide

1. Product Specifications & Comparative Analysis

2. Key Applications & Functional Insights

This small molecule inhibitor demonstrates exceptional performance in:

• Kinase inhibition studies (particularly FLT3 and JAK2 targets)
• Oncology research: Leukemia & myeloproliferative disease models
• Chemical biology probe development
• Structure-activity relationship (SAR) analysis

3. Operational Protocols & Best Practices

Recommended workflow:

1. Reconstitute in DMSO to 10mM stock concentration
2. Use within 6 months with proper storage
3. Cell-based assay concentration range: 1nM-10μM

4. Industry Case Studies

Case 1: Phase II kinase profiling in 293T cells showed 89% FLT3 inhibition at 100nM concentration.

Case 2: Achieved IC₅₀ of 23nM in MV4-11 cell proliferation assay.

5. Client Success Stories

PharmaTech Inc. (USA):

• Application: Acute myeloid leukemia drug discovery
• Result: Identified lead compound with 15x selectivity over JAK2

BioCore Research (Germany):

• Application: High-throughput kinase screening platform
• Result: Validated 3 novel kinase targets in 6-month study

6. Procurement Consultation

Contact our technical specialists for:

• Custom synthesis options
• Bulk pricing (10g+)
• MSDS & analytical data

Email: info@vivalr.com
Phone: (86) 15866781826