2-METHYL-6-NITROQUINOLINE

Comprehensive Guide to 2-Methyl-6-Nitroquinoline

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Industry Uses
• 3. Usage Scenarios & Best Practices
• 4. Comparative Analysis with Similar Compounds
• 5. Verified Customer Case Studies
• 6. Request Customized Quotation

1. Product Overview & Specifications

2-Methyl-6-Nitroquinoline (CAS 20743-05-9) is a nitro-substituted quinoline derivative with molecular formula C₁₀H₈N₂O₂ and molecular weight 188.18 g/mol. This yellow crystalline powder exhibits high purity (≥98% by HPLC) and solubility in organic solvents like DMSO and ethanol.

2. Key Applications & Industry Uses

This compound serves critical roles in:

• Pharmaceutical Intermediates: Synthesis of antimalarial drugs and kinase inhibitors
• Organic Electronics: Precursor for conductive polymers in OLED manufacturing
• Agrochemical Research: Development of novel pesticide formulations

3. Usage Scenarios & Best Practices

Typical Reaction Workflow:

1. Weigh 2.5 mmol under inert atmosphere
2. Dissolve in anhydrous DCM (10 mL)
3. Add catalyst (0.1 eq) at -10°C
4. Monitor by TLC until completion

4. Comparative Analysis

5. Verified Customer Case Studies

Case 1: Oncology Research Institute

• Challenge: Required stable quinoline derivatives for PROTAC development
• Solution: Custom synthesis with 99.2% purity
• Outcome: Successful degradation of target proteins (DC50 = 3.2 nM)

Case 2: Electronic Materials Supplier

• Challenge: Needed electron-deficient monomers for charge transport layers
• Solution: Bulk supply with strict particle size distribution
• Outcome: Achieved 18% improvement in device efficiency

6. Request Customized Quotation

Contact our technical team for:

• Bulk pricing (1kg to ton quantities)
• Custom synthesis protocols
• Regulatory documentation support

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