7,8-Dihydroxyflavone CAS 38183-03-8

7,8-Dihydroxyflavone CAS 38183-03-8: Comprehensive Product Guide

Contents

• 1. Product Specifications & Comparative Analysis
• 2. Detailed Applications & Mechanisms
• 3. Application Scenarios in Research
• 4. Verified Customer Case Studies
• 5. Inquiry Guidance

1. Product Specifications & Comparative Analysis

2. Detailed Applications & Mechanisms

2.1 Neuroprotective Agent

7,8-Dihydroxyflavone demonstrates exceptional blood-brain barrier permeability, activating TrkB receptors with 10× higher specificity than BDNF in:

• Alzheimer’s disease models
• Parkinson’s disease research
• Stroke recovery studies

2.2 Anti-Inflammatory Applications

The compound inhibits NF-κB signaling at IC₅₀ = 3.2 μM, making it effective for:

• Rheumatoid arthritis research
• Inflammatory bowel disease models

3. Application Scenarios in Research

3.1 In Vitro Neuroprotection Protocol

Typical experimental parameters:

4. Verified Customer Case Studies

4.1 University Neuroscience Research

A Tier 1 research institution achieved 42% reduction in amyloid-β plaques using:

• Dosage: 5 mg/kg/day
• Administration: Intraperitoneal
• Duration: 8 weeks

4.2 Pharmaceutical Development

European biotech company enhanced drug efficacy by 37% in Phase II trials through:

• Formulation: Liposomal encapsulation
• Bioavailability: Increased from 12% to 58%

5. Inquiry Guidance

Contact our technical specialists for:

• Custom synthesis (1g-100kg scale)
• Bulk pricing (≥500g orders)
• COA/MSDS documentation

Email: info@vivalr.com
Phone: (86) 15866781826

Request Sample: Specify required quantity (10mg-1g available) and intended application for optimized formulation guidance.