6-Bromoimidazo[1,2-a]pyridine (CAS 1072-56-0) is a brominated heterocyclic compound widely used in pharmaceutical synthesis and materials science.
Parameter | Specification |
---|---|
Molecular Formula | C7H5BrN2 |
Molecular Weight | 213.03 g/mol |
Appearance | White to off-white crystalline powder |
Purity | ≥98% (HPLC) |
Storage | 2-8°C in dry environment |
Primary applications include:
Aspect | Requirements |
---|---|
Handling | Use PPE (gloves, goggles) in fume hood |
Solubility | Soluble in DCM, DMF; sparingly in water |
Stability | Stable under inert atmosphere |
Disposal | Follow local hazardous waste regulations |
Compound | Reactivity | Cost Efficiency | Application Range |
---|---|---|---|
6-Bromoimidazo[1,2-a]pyridine | High | ★★★★☆ | Broad |
6-Chloro Derivative | Medium | ★★★★★ | Limited |
Unsubstituted Imidazopyridine | Low | ★★★☆☆ | Niche |
Case 1: Used as key intermediate in synthesis of preclinical cancer therapeutic DGX-203 (2023 study).
Case 2: Enabled 35% yield improvement in Suzuki-Miyaura coupling for OLED emitter production.
Client A: European Pharma Company
- Application: Developed BTK inhibitor using bromoimidazopyridine core
- Result: Achieved 90% purity in final API
Client B: Asian Materials Lab
- Application: Created blue-emitting OLED materials
- Result: Enhanced device lifetime by 40%
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