3-Hydroxypyridine-4-carboxaldehyde

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3-Hydroxypyridine-4-carboxaldehyde: Comprehensive User Guide

1. Product Overview & Specifications

3-Hydroxypyridine-4-carboxaldehyde (CAS 1072-23-9) is a high-purity chemical intermediate widely used in pharmaceutical synthesis, agrochemicals, and materials science. Key parameters:

Parameter Specification
Molecular Formula C6H5NO2
Molecular Weight 123.11 g/mol
Purity ≥98% (HPLC)
Appearance Off-white to pale yellow crystalline powder
Storage 2-8°C, protected from light

2. Applications & Use Cases

2.1 Pharmaceutical Synthesis

Used as a key intermediate in anticancer drugs (e.g., kinase inhibitors) and antibiotics. Its aldehyde group enables efficient Schiff base formation for ligand coupling.

2.2 Material Science

Facilitates synthesis of metal-organic frameworks (MOFs) and conductive polymers due to its chelating properties.

2.3 Agrochemicals

Essential in creating fungicides and herbicides with enhanced bioactivity and environmental stability.

3. Comparative Analysis

Parameter 3-Hydroxypyridine-4-carboxaldehyde Pyridine-4-carboxaldehyde 5-Hydroxypyridine-3-carboxaldehyde
Reactivity High (dual functional groups) Moderate Moderate
Solubility DMSO, Ethanol Water, Ethanol DMSO
Pharma Applications ★★★★☆ ★★★☆☆ ★★☆☆☆

4. Client Case Studies

Case 1: Anticancer Drug Development

Client: Top 10 Global Pharma Company

Challenge: Low yield (32%) in kinase inhibitor intermediate synthesis.

Solution: Used 3-Hydroxypyridine-4-carboxaldehyde as coupling agent.

Result: Yield increased to 78%, reduced reaction time by 40%.

Case 2: MOF Production

Client: Advanced Materials Corp

Challenge: Unstable coordination polymers.

Solution: Integrated the compound as a structural linker.

Result: Achieved 99% crystallinity and 20% higher gas adsorption capacity.

5. Contact for Quotations

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Our advantages:

  • ISO-certified production
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  • 24/7 technical support

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