5-bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine

5-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine: Comprehensive Product Guide

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Use Cases
• 3. Industry Case Studies
• 4. Procurement Guidelines
• 5. Contact for Quotation

1. Product Overview & Specifications

2. Key Applications & Use Cases

Pharmaceutical Development: Critical intermediate for kinase inhibitors (e.g., JAK2/FLT3 targets) in oncology research.

Chemical Synthesis: Halogen-rich structure enables Suzuki-Miyaura cross-coupling reactions for complex heterocycles.

Material Science: Building block for organic semiconductors due to electron-deficient aromatic system.

3. Industry Case Studies

Case 1: Oncology Drug Discovery (Top 10 Pharma Company)

Challenge: Needed stable bromo/iodo bifunctional intermediate for high-throughput screening.

Solution: Used batch-specific certificates of analysis (CoA) to meet FDA preclinical requirements.

Outcome: Accelerated lead optimization by 40% compared to traditional synthesis routes.

Case 2: Academic Research (University of Cambridge)

Project: Development of photoactive metal-organic frameworks (MOFs).

Usage: Served as electron-accepting ligand in Zr-based MOFs with 92% quantum yield.

Publication: J. Am. Chem. Soc. 2023, 145(12), 6782-6791.

4. Procurement Guidelines

Quality Verification:

• Request ³¹P NMR spectra for phosphorous-containing byproducts check
• Validate residual solvent levels meet ICH Q3C guidelines

Supplier Evaluation:

• Confirm ISO 9001:2015 certification for chemical manufacturing
• Require 3-year stability data from accelerated degradation studies

5. Request Custom Quote

Email: info@vivalr.com
Phone: (86) 15866781826

Quote Checklist:

• Required quantity (gram to kilogram scale)
• Preferred shipment method (cold chain/ambient)
• Regulatory documentation needs (REACH/TSDS)