Parameter | 8-Hydroxyquinoline-7-carboxylic Acid | Standard 8-Hydroxyquinoline |
---|---|---|
CAS Number | 1078-56-2 | 148-24-3 |
Molecular Formula | C10H7NO3 | C9H7NO |
Purity Grade | ≥99.5% (Pharmaceutical Grade) | 98-99% (Industrial Grade) |
Water Solubility | 1.2 g/L (25°C) | 0.3 g/L (25°C) |
Key Advantage: Enhanced solubility and carboxyl functional group enable superior metal chelation capabilities compared to basic hydroxyquinoline derivatives.
• Intermediate for antiviral/antibacterial APIs
• Heavy metal detoxification agents
• Radiopharmaceutical chelating agent
• Fungicide synergist (enhances efficacy by 40-60%)
• Plant growth regulator carrier
• Soil remediation agent
• Corrosion inhibitor in cooling systems
• Analytical chemistry reagent for metal ion detection
• Polymer stabilizer in specialty plastics
Application | Recommended Concentration | Optimal pH Range |
---|---|---|
Pharmaceutical Synthesis | 0.5-2.0 mol% | 6.8-7.4 |
Agricultural Formulations | 0.1-0.3% w/w | 5.5-6.5 |
Industrial Processes | 50-200 ppm | 3.0-8.0 |
Client: European Pharma Manufacturer
Challenge: Improve yield of antiviral drug intermediate
Solution: 1.2 mol% additive in coupling reaction
Result: 22% yield increase, 35% reduction in metal catalyst usage
Client: US Agrochemical Company
Challenge: Improve systemic fungicide performance
Solution: 0.25% additive in triazole formulation
Result: 58% longer residual activity, 40% dosage reduction
"Using 8-hydroxyquinoline-7-carboxylic acid in our radiopharmaceutical production reduced purification steps from 5 to 2, cutting production costs by $420,000 annually while meeting strict USP <711> standards."
"Incorporating this compound in our nano-fungicide delivery system increased field efficacy against rice blast disease from 68% to 89%, generating $1.2M additional revenue in 2023."
"As polymer stabilizer, it extended our specialty plastic's UV resistance from 800 hrs to 1,500 hrs in ASTM G154 testing, achieving automotive OEM certification."
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