Contents
Propionyl Bromide (CAS 598-22-1) Technical Profile
Essential Chemical Properties
| Parameter | Specification |
|---|---|
| Chemical Formula | C₃H₅BrO |
| Molecular Weight | 136.98 g/mol |
| CAS Number | 598-22-1 |
| Appearance | Colorless to pale yellow liquid |
| Purity | ≥98% (GC analysis) |
| Boiling Point | 103-105°C |
| Density | 1.52 g/cm³ at 25°C |
Comparative Analysis: Acyl Bromides
| Compound | Reactivity | Stability | Typical Applications |
|---|---|---|---|
| Propionyl Bromide | High | Moisture-sensitive | Pharma intermediates, Specialty chems |
| Acetyl Bromide | Moderate | Air-sensitive | Organic synthesis |
| Butyryl Bromide | Medium | Thermally stable | Polymer production |
Industrial Applications Breakdown
Pharmaceutical Manufacturing
Key intermediate in synthesis of:
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Antihypertensive active ingredients
- Antipsychotic medication precursors
Agrochemical Production
- Herbicide intermediate for crop protection
- Fungicide formulation component
Advanced Material Synthesis
- Liquid crystal production
- Polymer modification agent
Operational Protocols
Storage Requirements
| Condition | Specification |
|---|---|
| Temperature | 2-8°C |
| Atmosphere | Inert gas (N₂/Ar) |
| Container | Amber glass bottles |
Safety Measures
- NEVER expose to water/moisture
- Use dry chemical extinguishers
- Mandatory PPE: Face shield, neoprene gloves
Sector-Specific Implementations
Pharma API Production
Used in continuous flow synthesis of Ketorolac Tromethamine (5 kg batch scale)
Advanced Polymer Modification
Improved thermal stability in polyimide membranes for gas separation
Verified Customer Implementations
Case 1: European Pharma Innovator
| Parameter | Detail |
|---|---|
| Application | Anticoagulant API synthesis |
| Consumption | 850 kg/year |
| Result | 15% yield improvement vs traditional methods |
Case 2: Asian Agrochemical Leader
| Parameter | Detail |
|---|---|
| Application | Next-gen herbicide production |
| Scale | 12 MT annual usage |
| Benefit | Reduced synthesis steps from 5 to 3 |
Case 3: US Research Institute
| Parameter | Detail |
|---|---|
| Application | Conductive polymer R&D |
| Result | 3 patent filings in 2023 |
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